Alt-R™ CRISPR HDR Design Tool
A complete solution for high HDR rates based on wet bench testing and customer validation
Design and order HDR donor templates and associated Cas9 guide RNAs for genome editing of human, mouse, rat, zebrafish, or C. elegans targets.
- Better donor HDR template design and Cas9 guide RNA selection
- Flexible input and CRISPR HDR design parameters
- High HDR rates with Alt-R HDR Donor Oligos and Donor Blocks.
Research-friendly UX
The Alt-R CRISPR HDR Design Tool provides exceptional flexibility for seamless homology directed repair (HDR) design.
- Multiple input formats (gene name, accession number, genomic coordinates, sequence in FASTA format)
- Multiple species (human, mouse, rat, zebra fish, and C. elegans)
- Insertion, deletion, SNP, and amino acid mutations
- Silent mutation and custom tag addition
- Wild type/HiFi Cas9 or nickase designs
- Single or multiple design entry
Prof. Izuho Hatada
Genome Science Institute for Molecular and Cellular Regulation
Gunma University
Genome Science Institute for Molecular and Cellular Regulation
Gunma University
Using electroporation, integration rate we observed with an IDT’s Alt-R HDR donor oligo was significantly higher than integration rate obtained with the unmodified ssODN donor in mouse early embryos.
Resources
Brochures and flyers
Glossary
User guides and protocols
RUO22-1235_001