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Alt-R™ CRISPR HDR Design Tool

A complete solution for high HDR rates based on wet bench testing and customer validation

Design and order HDR donor templates and associated Cas9 guide RNAs for genome editing of human, mouse, rat, zebrafish, or C. elegans targets.

Better donor HDR template design and Cas9 guide RNA selection
Flexible input and CRISPR HDR design parameters
High HDR rates with Alt-R HDR Donor Oligos and Donor Blocks.

Research-friendly UX

The Alt-R CRISPR HDR Design Tool provides exceptional flexibility for seamless homology directed repair (HDR) design.

Multiple input formats (gene name, accession number, genomic coordinates, sequence in FASTA format)
Multiple species (human, mouse, rat, zebra fish, and C. elegans)
Insertion, deletion, SNP, and amino acid mutations
Silent mutation and custom tag addition
Wild type/HiFi Cas9 or nickase designs
Single or multiple design entry

Alt-R CRISPR HDR Design Tool Screenshot

Streamlined CRISPR-Cas9 HDR with an intelligent and easy-to-use design tool

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Flexible input

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Optimized HDR template design

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High HDR rates

Ready to get started?

Sign-in or create an IDT account to start using the Alt-R™ CRISPR HDR Design Tool today!

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Prof. Izuho Hatada
Genome Science Institute for Molecular and Cellular Regulation
Gunma University

Using electroporation, integration rate we observed with an IDT’s Alt-R HDR donor oligo was significantly higher than integration rate obtained with the unmodified ssODN donor in mouse early embryos.

Resources

RUO22-1235_001